-Ketoglutaric Acid (AKG)
AKG ua dab tsi rau lub cev?
AKG ( -Ketoglutaric Acid) yog ib yam khoom hauv tib neeg lub cev, thiab nws cov txiaj ntsig tseem ceeb rau lub cev yog yooj yim to taub:
Boosts zog:Nws pab hloov cov suab thaj, rog thiab protein peb noj rau hauv lub zog uas
hlwb tuaj yeem siv ncaj qha, txo qhov qaug zog thiab ua kom koj muaj zog.
Txhawb kev tiv thaiv -aging:Nws activates cellular autophagy kom tshem tawm puas "cell khib nyiab"
thiab tshem tawm cov teeb meem dawb radicals, slows cellular aging.
Pab metabolism:Nws pab tswj lub cev metabolic tshuav nyiaj li cas thiab txhawb nqa lub
ib txwm ua haujlwm ntawm cov hlwb thiab cov kabmob.
Tiv thaiv cov cell:Nws txhawb kev kho thiab kev noj qab haus huv ntawm lub cev hlwb, pab tswj
tag nrho lub cev zoo- nyob.
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Khoom npe: |
-Ketoglutaric acid (AKG)
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Synonyms: |
2-Oxoglutaric acid; 2-Oxopentanedioic acid; 2-Ketoglutaric acid |
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Formula: |
C5H6O5 |
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Molecular Luj: |
146.10 |
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CAS nr: |
328-50-7 |
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Qhov tshwm sim |
Dawb los yog yuav luag -dawb crystalline hmoov, tasteless thiab tsw |
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Kev ntsuam xyuas: |
> 98% |
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Kev xa tawm: |
NWS 95.00% |
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Loss ntawm ziab: |
1.00% NMT |
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Residue ntawm ignition: |
0.20% NMT |
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MOQ: |
1kg ua |
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Ntawv pov thawj: |
ISO9001, FSSC22000, Organic |
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Pob: |
25kg / Carton lossis customized |
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Lub neej txee: |
24 Lub Hlis nyob rau hauv chav tsev kub |
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Daim ntawv thov |
Khoom noj khoom haus additive, zaub mov additive, pub additive, Cosmetic |
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Cia: |
Khaws rau hauv lub qhov dej- kaw kom deb ntawm cov dej noo thiab tshav ntuj ncaj qha. |
Mechanism ntawm Action
-Ketoglutaric acid (AKG) yog lub ntuj nruab nrab ntawm lub zog- tsim Krebs lub voj voog, pab cov hlwb hloov zaub mov rau hauv lub zog siv tau (ATP). Nws kuj captures thiab detoxifies teeb meem ammonia generated los ntawm cov protein puas, hloov mus rau hauv cov khoom tsis muaj teeb meem. Tsis tas li ntawd, AKG txhawb kev tsim cov amino acids tseem ceeb (xws li glutamine thiab arginine) thiab ua kom muaj kev tiv thaiv kab mob antioxidant (SIRT1/Nrf2) uas txo cov oxidative kev nyuaj siab thiab kev laus qeeb.
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Cov yam ntxwv ntawm cov khoom |
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Khoom npe |
-Ketoglutaric Acid (AKG)/a-ketoglutarate |
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Synonyms: |
2-Oxoglutaric acid; 2-Oxopentanedioic acid; 2-Ketoglutaric acid |
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Formula: |
C5H6O5 |
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Molecular: |
146.10 |
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Qauv: |
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CAS Nr. |
328-50-7 |
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Khoom profile |
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Nqe lus piav qhia: |
Dawb los yog yuav luag -dawb crystalline hmoov, tasteless thiab tsw |
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Kev xa tawm: |
NWS 95.00% |
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Loss ntawm ziab: |
1.00% NMT |
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Residue ntawm ignition: |
0.20% NMT |
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Chloride: |
NMT 0.02% |
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Sulfate Radicals: |
0.20% NMT |
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Hlau: |
NMT 30.00 ppm |
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Heavy hlau: |
NMT 10.00 ppm |
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Arsenic: |
NMT 1.00 ppm |
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Kev ntsuam xyuas: |
NWS 98.00% |
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Tag nrho cov phaj suav: |
NMT 1,000 cfu/g |
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Pwm thiab Pwm: |
NMT 100 cfu/g |
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Coliforms: |
NMT 10 cfu/g |
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E.Coli: |
Tsis muaj / g |
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Salmonella: |
Tsis muaj / g |
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Ntim |
25kg / thawv |
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Cia |
Khaws cov khoom nyob rau hauv qhov chaw txias & qhuav thiab tsis txhob raug tshav ntuj |
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Txee lub neej |
24 lub hlis nrog ntim tsis tau qhib |
1.Kev Noj Qab Haus Huv Kev Noj Qab Haus Huv & Kev Ua Si
Qhov chaw:AKG yog ib qho tseem ceeb ntawm cov khoom noj khoom haus ua kis las thiab cov khoom noj qab haus huv. Nws txo cov ammonia toxicity thaum lub sij hawm qoj ib ce los ntawm kev khi ntau dhau ammonia thiab koom nrog nitrogen metabolism, thaum txhawb cov leeg kho thiab kev loj hlob. Piv nrog taurine, AKG ncaj qha ntxiv zog ua lub voj voog TCA tseem ceeb nruab nrab; nws cov formulation tsis muaj suab thaj, uas yog qhov zoo dua rau kev txo cov rog thiab cov leeg nqaij. Cov kev tshawb fawb tsiaj pom tau hais tias AKG txhim kho cov leeg nqaij, ua kom muaj zog, tuav lub zog, thiab ua kom txias, tiv thaiv hnub nyoog ntsig txog sarcopenia.
2.Kev lag luam zaub mov
Qhov chaw:AKG yog siv los ua cov khoom noj ntxiv nrog ob lub zog - kev txhim kho tsw thiab khaws cia - ua lub luag haujlwm hauv kev txhim kho saj thiab txuas lub neej txee.
3. Tshuaj pleev ib ce & Skincare
Qhov chaw:Siv rau nws cov khoom antioxidant hauv cov khoom tu tawv nqaij los txhawb kev noj qab haus huv ntawm daim tawv nqaij, txo cov tsos mob ntawm kev laus, thiab ua rau deodorant (txo lossis npog lub cev tsw).
Cov ntaub ntawv tshawb fawb:
Moisturizing & anti wrinkle:Ib qho tshuaj tiv thaiv kev laus uas muaj KG pom muaj txiaj ntsig zoo ntawm daim tawv nqaij hydration thiab kev ua haujlwm tsis zoo. Fermented mov kua uas muaj KG ua kom cov tawv nqaij zoo dua qub thiab tiv thaiv wrinkle muaj nuj nqi hauv kev sim tshuaj.
Reduces wrinkle tsim:KG nce collagen ntau lawm los ntawm activating prolidase txoj kev, yog li txo UVB induced wrinkle tsim.
4.Tsiaj Khoom Noj & Pub
Qhov chaw:AKG qhia tau hais tias muaj peev xwm zoo hauv cov khoom noj tsiaj vim nws lub luag haujlwm hauv lub zog metabolism, tiv thaiv antioxidant, tiv thaiv kev ua haujlwm, thiab kev tiv thaiv kab mob.
Cov ntaub ntawv tshawb fawb:
Weaned piglets:Ntxiv 500-1000 g / tuj AKG rau cov khoom noj kom txo tau qhov mob raws plab, txhim kho cov zaub mov digestibility thiab kev siv cov amino acid, thiab txhim kho kev noj qab haus huv tag nrho.
Luav plaub hau follicle kev loj hlob:AKG supplementation txhawb txoj kev loj hlob ntawm cov plaub hau follicle thiab txhim kho kev ua tau zoo thiab muaj peev xwm antioxidant.
Anti metabolic stress:AKG alleviates oxidative kev nyuaj siab vim los ntawm cov rog / siab fructose noj thiab hloov kho hematological tsis nyob rau hauv cov ntaub so ntswg dependent thiab noj zaub mov.
5.Pharmaceutical Intermediates & Organic Synthesis
AKG yog dav siv los ua tshuaj nruab nrab thiab hauv cov organic synthesis thiab tshuaj zoo. Nws ua haujlwm ua ntej rau kev sib txuas ntawm ntau yam amino acids, carbohydrates, thiab cov proteins, nrog rau kev siv dav hauv cov zaub mov, tshuaj, khoom noj, thiab tshuaj lom neeg kev lag luam.
AKG yog ib qho metabolite tshwm sim hauv cov kab mob nyob. Nyob rau hauv qhov kev txiav txim ntau npaum li cas, nws yog qhov tseem ceeb tsis muaj tshuaj lom thiab tsis nce nitrogen load. Nws yog ib qho tsis muaj tshuaj lom luv luv saw carboxylic acid nrog kev ruaj ntseg siab hauv cov tshuaj aqueous.
1 Ntuj Keeb Kwm & Kev Nyab Xeeb
AKG yog ib qho metabolite tshwm sim hauv cov kab mob nyob. Hauv qhov ntau npaum li cas, nws yog qhov tseem ceeb tsis yog - lom thiab tsis nce nitrogen load. Nws yog ib qho uas tsis yog - tshuaj lom luv luv - saw carboxylic acid nrog kev ruaj ntseg siab hauv cov tshuaj aqueous.
2 Siab Solubility & Bioavailability
AKG nthuav tawm cov kua dej ntau heev hauv dej (kwv yees . 200 mg/mL) thiab yaj sai sai hauv cov kua dej. Raws li cov dej- cov khoom soluble, AKG tsis tas yuav tsum tau noj nrog cov zaub mov kom nqus tau zoo, muab cov txiaj ntsig tseem ceeb hauv cov khoom noj thiab cov khoom noj ua haujlwm.
3 Ntau Txoj Kev Ntau Lawm Muaj
AKG tuaj yeem tsim los ntawm kev siv tshuaj lom neeg, microbial fermentation, lossis tag nrho cov cell biotransformation.
Tshuaj synthesis- cov txheej txheem paub tab tab sis nyuaj, tus nqi siab, thiab kev txhawj xeeb ib puag ncig.
Microbial fermentation- environmentally friendly tab sis tsis tshua muaj txiaj ntsig thiab purity.
Tag nrho -cell biotransformation – eco-friendly, high specificity, safe. Using L-glutamic acid as substrate, AKG yield can reach 180 g/L with a molar yield >95%, qhia txog kev siv tau zoo heev.
Q1: Dab tsi yog -Ketoglutaric acid?
-Ketoglutaric acid (AKG) yog cov organic acid uas tshwm sim nyob rau hauv cov kab mob uas muaj sia nyob thiab ib qho tseem ceeb metabolic nruab nrab ntawm TCA (Krebs) lub voj voog. Nws ua lub luag haujlwm tseem ceeb hauv kev tsim hluav taws xob ntawm tes, amino acid metabolism, ammonia detoxification, thiab antioxidant tiv thaiv, tau txais nws cov lus piav qhia "lub hub txuas carbon thiab nitrogen metabolism."
Q2: Puas yog AKG muaj nyob hauv tib neeg lub cev?
Yog lawm, AKG yog cov metabolite hauv tib neeg lub hlwb, ua ke hauv ntau cov ntaub so ntswg nrog rau daim siab, cov leeg pob txha, thiab lub hlwb. Raws li ib txwm nruab nrab ntawm TCA lub voj voog, nws koom nrog hauv txhua hnub lub zog metabolism.
Q3: Qhov txawv ntawm AKG thiab ornithine - -ketoglutarate (OKG) yog dab tsi?
AKG thiab OKG yog qhov sib txawv. AKG yog cov kua qaub dawb ntawm ketoglutaric acid; OKG yog ntsev tsim ntawm ornithine thiab ketoglutaric acid. Lawv txawv hauv cov txheej txheem metabolic thiab kev siv tshuaj kho mob thiab yuav tsum tsis txhob tsis meej pem.
Cim npe nrov: -ketoglutaric acid (akg), Tuam Tshoj -ketoglutaric acid (akg) manufacturers, lwm tus neeg, Hoobkas
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