Heme Hlau

Cov hlau twg zoo dua, heme lossis tsis yog -heme?

Piv nrog rau cov hlau tsis muaj heme, heme hlau muaj qhov zoo dua, nrog kev nqus zoo dua thiab ntau dua bioavailability, thiab tuaj yeem pab tib neeg lub cev nce cov ntsiab lus hlau. Txawm li cas los xij, tsis yog heme hlau muab tau los ntawm cov nroj tsuag kuj tseem ceeb. Nws yog ib qho tsim nyog sau cia tias muaj kev sib koom ua ke ntawm heme hlau thiab muaj kev pheej hmoo ntawm kev mob qog noj ntshav, yog li kev noj cov nqaij liab yuav tsum tau tswj nyob rau hauv qhov tsim nyog. Heme hlau los ntawm cov tsiaj txhu xws li nqaij, nqaij qaib, thiab ntses muaj qhov nqus ntawm 15% thiab 35%; Qhov nqus ntawm cov hlau tsis muaj heme los ntawm cov nroj tsuag xws li taum, zaub, thiab nplej yog qhov tsawg, tsuas yog 2% -20%. Tab sis yog tias cov khoom noj cog qoob loo tau noj ua ke nrog cov nqaij, "cov khoom noj nqaij" tuaj yeem txhim kho kev nqus ntawm cov hlau tsis muaj heme.

Mechanism ntawm kev ua:

Absorption Pathway (Tshwj xeeb rau Heme Hlau)
Heme hlau siv ib qho tshwj xeeb, muaj txiaj ntsig zoo nqus cov tshuab sib txawv ntawm cov tsis yog -heme hlau ntsev .

Intact Uptake: Lub nplhaib porphyrin tso cai rau heme coj los ntawm enterocytes ua ib qho tsis zoo metalloporphyrin ntawmheme carrier protein 1 (HCP1) .

Kev zam ntawm Barriers: Nws bypasses qhov xav tau rau:

Gastric acid txo (Fe3+ → Fe2+ conversion)

Kev sib tw nrog kev noj zaub mov inhibitors (phytates, polyphenols, oxalates)

Sab Hauv Tso: Hauv cov enterocyte, hlau raug tso tawm los ntawm lub nplhaib heme los ntawm heme oxygenase.

Sib koom Efflux: Cov hlau dawb ces nkag mus rau txoj hauv kev ntawmferroportin uanyob rau hauv kev, khi rau transferrin.

Heme hlau feem ntau yog tsim rau plaub pawg ntawm cov khoom vim nws qhov nqus tau siab thiab qis plab hnyuv: cov khoom noj khoom haus, cov khoom noj ntxiv thiab cov zaub mov tsim nyog rau cov menyuam mos thiab cov menyuam yaus, cov khoom noj khoom haus thiab dej haus rau cov pej xeem, thiab cov zaub mov tshwj xeeb kho mob rau cov neeg tshwj xeeb.

Kev noj zaub mov ntxiv: Cov khoom lag luam no yog cov ntawv thov tseem ceeb rau heme hlau, nrog lub hom phiaj tseem ceeb ntawm kev muab cov khoom siv hlau zoo rau ntau pab pawg neeg uas xav tau cov hlau ntxiv sai thiab meej, zam qhov tsis zoo ntawm qhov nqus nqus tsawg thiab plab hnyuv plab ntawm cov tshuaj hlau ib txwm muaj.

Cov khoom siv hlau, xws li heme hlau ntsiav tshuaj, tshuaj ntsiav, thiab cov kua hauv qhov ncauj, tuaj yeem ua nrog siab -purity heme hlau raws li cov khoom tseem ceeb ib leeg, lossis ua ke nrog cov vitamin C, folic acid, thiab lwm yam khoom xyaw ntxiv txhawm rau txhim kho hlau nqus thiab pab hematopoiesis. Lawv tsim nyog rau cov neeg uas tsis muaj hlau tsis muaj ntshav liab, cov poj niam cev xeeb tub / lactating, poj niam cev xeeb tub, thiab lwm tus neeg. Lawv yog ib qho yooj yim mus noj thiab cov tshuaj yog tswj tau.

Compound nutrient supplements:xws li cov poj niam cev xeeb tub cov vitamins tshwj xeeb, cov txiv neej txoj kev loj hlob, thiab cov ntsiav tshuaj ntau yam rau nruab nrab - cov neeg laus thiab cov neeg laus, uas sib xyaw heme hlau nrog calcium, vitamin D, vitamin B thiab lwm yam khoom kom tau raws li kev noj zaub mov zoo ntawm cov theem tshwj xeeb ntawm lub cev lossis cov neeg tshwj xeeb, tshwj xeeb tshaj yog tsim rau cov poj niam cev xeeb tub (kev txhawb nqa cov hlau thiab folic acid) ntxiv rau lub sij hawm loj hlob ntawm cov hlau thiab folic acid.

Portable supplements:xws li heme hlau hmoov thiab cov ntsiav tshuaj chewable, haum rau cov neeg uas tsis yooj yim rau noj cov tshuaj ntsiav / ntsiav tshuaj tsis tu ncua, xws li cov neeg ua haujlwm hauv chaw ua haujlwm thiab cov tub ntxhais kawm. Lawv tuaj yeem raug coj ncaj qha lossis diluted, sib npaug yooj yim thiab cov nyhuv hlau ntxiv. Cov saj yog me me thiab tsis yooj yim ua rau tsis xis nyob xws li xeev siab thiab cem quav.

Cov me nyuam mos thiab cov me nyuam me muaj cov khoom noj ntxiv thiab cov khoom noj mis

Cov me nyuam mos thiab cov me nyuam yaus (0-3 xyoos) loj hlob thiab loj hlob sai, nrog rau kev xav tau ntawm cov hlau tsis muaj zog thiab lub plab zom mov tsis zoo. Tsis yog heme hlau nqus yog nyuaj thiab yooj yim irritates cov hnyuv thiab plab. Qhov me me thiab qhov nqus tau siab ntawm heme hlau ua rau nws nyiam cov hlau rau cov khoom zoo li no, thiab nws yuav tsum ua raws li cov qauv kev nyab xeeb khoom noj rau menyuam mos thiab menyuam yaus.

Formula zaub mov rau kev kho mob tshwj xeeb

Cov khoom no yog tsim los rau cov neeg uas muaj cov kab mob tshwj xeeb lossis cov kab mob physiological, thiab yuav tsum tau ua kom tau raws li cov kev xav tau ntawm cov hlau zoo. Nws tseem yuav tsum tau ua raws li cov qauv tsim nyog rau cov khoom noj siv kho mob tshwj xeeb thiab siv raws li kev taw qhia ntawm cov chaw tshaj lij lossis kws kho mob.

Cov zaub mov tshwj xeeb ntawm anemia:xws li kev hloov pluas noj thiab cov khoom noj khoom haus rau cov neeg mob ntshav qab zib tsis muaj hlau, nrog heme hlau ua cov khoom tseem ceeb ntawm cov hlau ntxiv, ua ke nrog folic acid, vitamin B12 thiab lwm yam khoom xyaw uas xav tau rau hematopoiesis, txhawm rau ntxiv cov hlau reserves sai, pab txhim kho cov tsos mob ntshav qab zib, thiab hloov mus rau cov kab mob ntshav qab zib uas tshwm sim los ntawm kev mob plab hnyuv thiab lwm yam kab mob.

Postoperative thiab rehabilitation tshwj xeeb cov zaub mov:xws li kev noj zaub mov zoo rau kev phais plab hnyuv thiab kev rov qab los ntawm cov kab mob loj, ntxiv nrog cov nqi tsim nyog ntawm heme hlau, tsis muaj kev vam khom rau kev hloov pauv ntawm gastric acid.

-Tus nqi siab:
Qhov nqus tau tuaj yeem ncav cuag 15% -35%, ntau dua li cov hlau tsis muaj heme los ntawm cov nroj tsuag (tsuas yog 5% -8%), thiab cov txheej txheem nqus dej tsis cuam tshuam los ntawm cov kua qaub kua qaub, cov khoom xws li oxalic acid, phosphate, tannins hauv cov zaub mov, thiab cov khoom hlau, ua rau cov neeg muaj zog gastrointestinal.

-Kev txhawb nqa me me thiab qis:
Tsis muaj zog hlau lossis hlau tsis hnov ​​tsw, tsuas yog me ntsis hlau tsis hnov ​​tsw, zoo dua rau cov hlau tsis muaj zog xws li ferrous sulfate. Tom qab noj nws, yuav luag tsis muaj qhov tsis xis nyob hauv plab xws li xeev siab, tsam plab, raws plab, cem quav, thiab lwm yam. Nws muaj peev xwm ua tau zoo heev thiab tsim nyog rau lub sijhawm ntev - ntxiv.

-High purity adaptability:
Raws li daim ntawv thov, nws muab faib ua qib zaub mov (purity Ntau dua lossis sib npaug li 95%), qib kev noj qab haus huv (purity Ntau dua lossis sib npaug li 95%), thiab qib pub (purity Ntau dua lossis sib npaug li 85%). Ntawm lawv, qib zaub mov / qib kev noj qab haus huv yog qhov sib sib zog nqus tsaus liab zoo crystalline hmoov nrog zoo fluidity thiab tsis muaj clumping. Tom qab dissolving nyob rau hauv dilute hydrochloric acid, nws ua ib tug cherry liab pob tshab kua; Cov qib pub yog cov hmoov xim av dub, tso cai rau me me ntawm hemoglobin impurities nyob twj ywm yam tsis muaj kev cuam tshuam rau cov hlau supplementation muaj nuj nqi; Cov khoom tsis zoo uas tsis zoo yog feem ntau grey dub, clumped, nrog lub zog hlau tsis hnov ​​tsw thiab tsis tshua muaj bioavailability.

-Qhov chaw nyab xeeb thiab tswj tau:
Zoo heme hlau yog los ntawm cov tsiaj cov ntshav uas tau raug cais tawm thiab pom zoo (xws li cov ntshav npua tuaj ntawm Denmark). Nws cov qauv hemoglobin yuav luag zoo ib yam rau tib neeg cov ntshav thiab tuaj yeem lees paub ncaj qha thiab siv los ntawm tib neeg lub cev. Tsis muaj contraindications rau noj (tshwj tsis yog rau cov neeg tsis muaj hlau tsis muaj ntshav liab). Qee cov khoom lag luam muaj cov ntsiab lus protein ntau dua 70%, thiab cov khoom siv hlau ntxiv tuaj yeem ntxiv cov khoom me me ntawm cov protein zoo.

-Clear zaub mov muaj nuj nqi:
Ntxiv nrog rau kev ntxiv cov hlau, nws tuaj yeem koom nrog ntau yam txheej txheem physiological hauv lub cev, suav nrog kev thauj cov pa oxygen thiab kev sib pauv, cov ntaub so ntswg ua pa, hloov pauv ntawm beta carotene rau hauv vitamin A, antibody ntau lawm, tshuaj siab detoxification, thiab lipid ntshav thauj. Nyob rau tib lub sijhawm, nws tuaj yeem siv los ua ib feem ntawm catalase kom tshem tawm hydrogen peroxide hauv lub cev thiab pab txhim kho lub cev tiv thaiv kab mob.

Q1. Heme Iron yog dab tsi?

A1: Heme hlau yog ib hom hlau uas muaj nyob rau hauv cov tsiaj derived cov khoom noj (cov nqaij liab, tsiaj siab, tsiaj ntshav, nqaij qaib, thiab ntses) nyob rau hauv cov xwm. Nws kuj tseem yog qhov tseem ceeb tshaj plaws rau tib neeg cov hlau ntxiv thiab tuaj yeem muab rho tawm lossis ua tiav rau hauv cov khoom noj khoom haus, khoom noj khoom haus fortified raw cov ntaub ntawv, thiab lwm yam khoom cov ntaub ntawv los ntawm siab - purity ua. Nws cov txiaj ntsig tseem ceeb yog nyob rau hauv siab bioavailability thiab zoo nqus cov yam ntxwv. Tsis zoo li cov hlau tsis muaj heme los ntawm cov nroj tsuag, nws tuaj yeem siv los ntawm tib neeg lub cev yam tsis muaj kev hloov pauv thiab tsim nyog rau lub cev xav tau ntawm ntau hom hlau ntxiv.

Q2: Cov neeg tsis noj nqaij puas tuaj yeem noj heme hlau?
A2: Tsis yog. Standard heme hlau polypeptide yog muab los ntawm bovine (nyuj) cov qe ntshav liab. Nws tsis haum rau cov neeg tsis noj nqaij lossis vegans

Q3: Puas yog heme hlau zoo dua li cov tshuaj hlau niaj hnub?
A3: Rau kev zam: Yog. High-zoo meta- kev tshuaj ntsuam qhia pom tias heme hlau ua rau muaj kev phiv hauv plab hnyuv tsawg dua li tsis yog- heme ntsev .
Rau kev ua tau zoo: Hauv cov neeg laus feem ntau, ob qho tib si yog qhov tsis txaus. Txawm li cas los xij, heme hlau tuaj yeem ua tau zoo tshaj rau kev txhawb nqa hemoglobin tshwj xeeb hauv cov menyuam yaus uas muaj ntshav qab zib.

Hu rau tam sim no

Cim npe nrov: Tuam Tshoj heme hlau manufacturers, lwm tus neeg, Hoobkas